Solid matrix for the storage of biological samples
AssigneeGe Healthcare UK Limited
InventorsHUGH O'MALLEY, BARRY JOHNSON
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Abstract
The present invention relates to a method for storage and subsequent lysis of a sample in which the sample is immobilized on a solid support. The solid matrix is embedded with a low concentration of both a chaotropic salt and a surfactant which act synergistically to efficiently store and lyse a biological sample.
Claims30
A solid matrix for storing and/or lysing a biological sample comprising a surfactant and a chaotropic salt, wherein the concentration of the chaotropic salt is less than 0.5M.
A method of storing and/or lysing a biological sample comprising the steps:
- i) contacting a solid matrix of any preceding claim with a biological sample;
- and
- ii) storing said solid matrix with said biological sample,
- wherein the chaotropic salt and surfactant have a synergistic effect in lysing the cell.
A method of manufacturing a solid matrix comprising the steps:
- i) dipping a solid matrix into a mixture of a surfactant and a chaotropic salt wherein the concentration of said chaotropic salt is less than 0.5M;
- and
- ii) allowing the solid matrix to dry.
Dependencies are inferred from the claim text.