Method and system to predict ssri response
AssigneePathway Genomics
InventorsCindy Wang, Tanya Moreno, K. David Becker
Life of this patent
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Abstract
The present inventions relates to methods and assays to predict the response of an individual to an SSRI treatment and to a method to improve medical treatment of a disorder, which is responsive to treatment with a selective serotonin reuptake inhibitor (SSRI).
Claims24
A method for determining an individual's response to selective serotonin reuptake inhibitor (SSRI) treatment, comprising genotyping the individual for the presence of homozygous L alleles in the 5-HTTLPR in the SLC6A4 serotonin transporter gene, and characterizing that individual's response to SSRI treatment based on the presence of said L alleles.
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A genetic test for assessing an individual's response to SSRI therapies, comprising a) a means for determining a genotype for said individual homozygous for the L allele with a probe specific to a 43 base-pair segment in the promoter region of the SLC6A4 gene having the sequence of SEQ ID NO:5.
Dependencies are inferred from the claim text.