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US 2014/0272232 A1Published application
Antithrombic coatings and uses thereof
OwnerGiridhar Thiagarajaninventor
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Abstract
Provided are multi-layer antithrombic coatings comprising an outermost layer of an antithrombic agent, such as a heparin conjugate, bound to a penultimate polymeric layer comprising cationic polymer species that is bound alternating polymeric layers comprising anionic polymer species and cationic polymer species, and uses thereof.
Claims20
An antithrombic coating, comprising
- a) a substrate;
- b) a first polymeric layer comprising synthetic cationic polymer species bound to said substrate;
- c) a second polymeric layer comprising synthetic anionic polymer species interacting electrostatically with said first polymeric layer;
- d) a penultimate polymeric layer comprising synthetic cationic polymer species interacting electrostatically with said second polymeric layer;
- and
- e) an outer layer comprising an anionic antithrombic agent interacting electrostatically with said penultimate polymeric layer.
3 more elements
Dependencies are inferred from the claim text.