Biocompatible fiber textiles for implantation
AssigneeNanofiber Solutions, LLC
InventorJed JOHNSON
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Abstract
A biocompatible textile and methods for its use and fabrication are disclosed. The textile may be fabricated from electrospun fibers forming windings on a mandrel, in which the windings form openings having a mesh size between adjacent windings. The textile may also be fabricated by the addition of solvent-soluble particles incorporated into the textile while the windings are formed. Such particles may be removed by exposing the textile to a solvent, thereby dissolving them. Disclosed are also replacements for animal organs composed of material including at least one layer of an electrospun fiber textile having a mesh size. Such replacements for animal organs may include biocompatible textiles treated with a surface treatment process.
Claims33
A biocompatible textile comprising:
- at least one electrospun fiber, comprising at least one polymer, disposed on a mandrel,
- wherein:
- the electrospun fiber forms a plurality of windings on the mandrel,
- each winding of the plurality of windings forms an opening with an adjacent winding, thereby forming a plurality of openings between a plurality of adjacent windings, and
- the plurality of openings comprises a mesh size.
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A biocompatible textile comprising:
- an at least one electrospun fiber, comprising at least one polymer, disposed longitudinally along a linear axis of a mandrel, thereby forming a plurality of textile threads, wherein:
- the at least one electrospun fiber forms openings between adjacent linearly deposited textile threads of a mesh size;
- and
- the plurality of openings comprises a mesh size.
A method for fabricating a biocompatible textile comprising:
- electrospinning a biocompatible polymer into an electrospun fiber;
- contacting the electrospun fiber with a particulate material having a solubility in a solvent;
- contacting the electrospun fiber with a receiving surface, thereby forming a polymer network thereon comprising a plurality of electrospun fiber threads and a plurality of spaces between adjacent electrospun fiber threads;
- removing the polymer network from the receiving surface, thereby forming a biocompatible textile;
- and
- contacting the biocompatible textile with the solvent thereby removing the particulate material,
- wherein the plurality of openings comprises a mesh size.
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Dependencies are inferred from the claim text.