Modifying taste and sensory irritation of smokeless tobacco and non-tobacco products
AssigneeAltria Client Services LLC
InventorsGerd Kobal, Georgios D. Karles, Munmaya K. Mishra
Life of this patent
Estimating the term…
Abstract
Tobacco products comprising smokeless tobacco products and active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel are disclosed. Nicotine replacement therapies comprising active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel. The active ingredient may reduce or eliminate sensory irritation arising due to use of the product. Analgesic compositions comprising active ingredients. Methods of reducing taste and sensory irritation by employing an active ingredient.
Claims20
A tobacco product comprising:
- a smokeless tobacco product;
- at least one active ingredient wherein the active ingredient is selected from the group consisting of castor oil, ricinoleic acid, and conjugates or derivatives thereof,
- wherein the smokeless tobacco product is adapted to be chewed, sucked, or orally manipulated in a consumer's mouth.
A method of making a tobacco product comprising
- combining a smokeless tobacco product with at least one active ingredient that is an antagonist of at least one receptor selected from the list consisting of nicotinic acetylcholine receptors, the TRPV1 channel, and the TRPA1 channel,
- wherein the at least one active ingredient is present in an amount effective to reduce or eliminate sensory irritation arising due to use of the product and wherein the at least one active ingredient is a taste receptor blocker.
An analgesic composition comprising a therapeutically effective amount of an active ingredient wherein the active ingredient is selected from the list consisting of castor oil, hydrogenated ethoxylated glycerol ester, ricinoleic acid, esters of ricinoleic acid, ricinelaidic acid, ricinolein, isopropyl ricinoleate, sodium ricinoleate, phenylacetylricinoleic acid, polyglycerol polyricinoleate, and derivatives and/or combinations thereof.
A nicotine replacement therapy comprising a composition comprising a therapeutically effective amount of an active ingredient wherein the active ingredient is an antagonist of at least one receptor or channel selected from the list consisting of nicotinic acetylcholine receptors, the TRPV1 channel, and the TRPA1 channel.
A method of reducing taste and sensory irritation of a composition comprising
- combining the composition with an effective amount of an active ingredient that is selected from the list consisting of castor oil, ricinoleic acid, esters of ricinoleic acid, ricinelaidic acid, ricinolein, isopropyl ricinoleate, sodium ricinoleate, phenylacetylricinoleic acid, polyglycerol polyricinoleate, and derivatives and/or combinations thereof.
Dependencies are inferred from the claim text.