Management of Tractional Membranes
OwnerMark Humayuninventor
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Abstract
Methods and compositions are provided here to manage tractional membranes, as well as other diseases and disorders of the eye. Compositions comprising microbubbles associated with enzymes or vitreolytic agents, are provided. The method of the present invention involves administration of the microbubble and an enzyme or vitreolytic agent to a subject in need thereof, followed by application of ultrasound.
Claims23
A composition for comprising microbubbles associated one or more therapeutic agents selected from the group consisting of enzymes and non-enzymatic vitreolytic agents.
A method of treating a tractional membrane of the eye in a subject in need thereof comprising:
- (i) administering an effective amount of a composition comprising microbubbles to the tractional membrane of the eye in need of treatment, wherein the microbubbles are associated with one or more therapeutic agents selected from the group consisting of enzymes and non-enzymatic vitreolytic agents and (ii) applying ultrasound energy generated by an ultrasound probe to the eye, wherein the application of ultrasound energy is sufficient to activate the microbubble composition and treat the tractional membrane.
Dependencies are inferred from the claim text.