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US 2014/0271876 A1Published application
Ophthalmic formulations
AssigneeInotek Pharmaceuticals Corporation
InventorsWilliam K. MCVICAR, Harun TAKRURI
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Abstract
The present invention relates to an ophthalmic formulation which comprises a fine particle of Compound A in an aqueous suspension and a manufacturing process thereof. More specifically, the present invention relates to a topically applied ophthalmic aqueous suspension which is obtainable by suspending fine particles of Compound A in an aqueous vehicle containing a surfactant and boric acid. The invention also provides processes for making the ophthalmic formulations and to methods of use thereof.
Claims67
An ophthalmic formulation comprising:
- (a) an aqueous suspension of micronized Compound A from 0.1 to 5.0% (w/v),
- (b) a surfactant,
- (c) boric acid from about 0.05 to about 2.0% (w/v), and.
- (d) a buffering agent that maintains the pH from about 6.0 to about 7.0.
1 more element
Dependencies are inferred from the claim text.