Gastroretentive dosage system and process of preparation thereof
AssigneeRanbaxy Laboratories Limited
InventorsVarinder Kumar, Shavej Ahmad, Romi Barat Singh
Life of this patent
Estimating the term…
Abstract
The present invention relates to novel gastroretentive dosage systems, in particular, a floating capsule which releases the drug without any lag time and which remains buoyant for a sufficient period of time in the stomach. Further, the invention relates to the process of preparation thereof.
Claims10
A gastroretentive dosage system comprising:
- (a) a shell filled with the active ingredient in powder form;
- and
- (b) an extended-release layer over the shell.
A gastroretentive dosage system comprising:
- (a) a shell filled with the active ingredient in powder form;
- (b) an extended-release layer over the shell;
- and
- (c) an immediate-release layer comprising the active ingredient over the extended-release layer.
A process for the preparation of a gastroretentive dosage system, wherein the process comprises the steps of:
- (a) filling the empty shell with the active ingredient in powder form;
- and
- (b) coating the shell with a solution or dispersion of one or more extended-release polymer(s) and one or more coating additive(s).
A process for the preparation of a gastroretentive dosage system, wherein the process comprises the steps of:
- (a) filling the empty shell with the active ingredient in powder form;
- (b) coating the shell with a solution or dispersion of one or more extended-release polymer(s) and one or more coating additive(s);
- and
- (c) coating the above coated shells with a solution or dispersion of the active
Dependencies are inferred from the claim text.