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US 2014/0271838 A1Published application
Pharmaceutical soft gelatin capsule dosage form with modified guar gum
AssigneeAllergan Pharmaceuticals International Limited
InventorsBrendan MULDOON, Ryan Gerald LOUGHLIN, Gerarde SWEENEY, Emma Karen BOYD
Life of this patent
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Abstract
A pharmaceutical soft gelatin capsule dosage form that includes (a) a shell that includes gelatin; and (b) a fill that includes at least one active ingredient, one or more polyethylene glycol, and a modified guar gum. The pharmaceutical soft gelatin capsule dosage form maintains its shell integrity (hardness) and fill viscosity after storage.
Claims20
A pharmaceutical soft gelatin capsule dosage form comprising:
- a shell comprising gelatin and a plasticizer;
- and
- a fill comprising at least one pharmaceutically active ingredient, one or more polyethylene glycol, and a modified guar gum.
A pharmaceutical soft gelatin capsule dosage form comprising:
- a shell comprising gelatin and a plasticizer;
- and
- a fill comprising at least one pharmaceutically active ingredient, one or more polyethylene glycol, and a modified guar gum,
- wherein the fill after encapsulation has a log viscosity of about 1 to about 2 times greater than the log viscosity of the fill before encapsulation over a log shear rate of about −1.0 to about 1.0.
1 more element
Dependencies are inferred from the claim text.