Lipid vesicle compositions and methods of use
AssigneeMassachusetts Institute of Technology
InventorsDarrell J. Irvine, Jaehyun Moon
Life of this patent
Estimating the term…
Abstract
The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.
Claims25
1-52. (canceled)
A multilamellar lipid vesicle having at least two lipid bilayers covalently crosslinked to each other through headgroups that react with covalent crosslinkers to form covalent crosslinks between the at least two lipid bilayers, wherein the multilamellar lipid vesicle comprises an agent.
A composition comprising:
- a multilamellar lipid vesicle having at least two lipid bilayers covalently crosslinked to each other through headgroups that react with covalent crosslinkers to form covalent crosslinks between the at least two lipid bilayers;
- and
- an agent.
(canceled)
-70. (canceled)
-75. (canceled)
A method of delivering an agent to a subject comprising administering to a subject
- a multilamellar lipid vesicle having at least two lipid bilayers covalently crosslinked to each other through headgroups that react with covalent crosslinkers to form covalent crosslinks between the at least two lipid bilayers;
- and
- an agent.
-80. (canceled)
Dependencies are inferred from the claim text.