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US 2014/0271784 A1Published application
Decellularized omentum matrix and uses thereof
AssigneeEhitcon, Inc.
InventorsChunlin Yang, Qiang Zhang, Ilya Koyfman, Ziwei Wang, Daphne Anne Salick Ryan, Robert B. Vetrecin, Philip M. Steele
Life of this patent
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Abstract
Methods for defatting omentum and processes for preparing an acellular omentum, i.e., devitalized or decellularized omentum, comprising extracellular matrix for implantation into a mammalian system. Constructs for medical applications comprising decellularized omentum are also described. More specifically, mesh reinforced omentum biomatrix for soft tissue repair is described.
Claims19
A method for defatting omentum comprising:
- providing an omentum, dehydrating the omentum by freeze drying;
- a first defatting step comprising compressing the omentum at a temperature and pressure, for a sufficient amount of time to remove greater than 50 percent by weight of the fat from the omentum;
- a second defatting step comprising contacting the omentum with at least one extraction solvent and extracting the residual fat from the omentum to provide a defatted omentum having less than 5 percent by weight of fat.
Dependencies are inferred from the claim text.