Medical Device
AssigneeStemnion, Inc.
InventorsLarry R. Brown, George L. Sing
Life of this patent
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Abstract
The invention is directed to an improved medical device. In particular, the invention is directed to an improved medical device having a coating comprising novel cellular factor-containing solution compositions (referred to herein as CFS compositions), such CFS compositions including conditioned medium compositions obtained from culturing extraembryonic cytokine secreting cells (ECS cells), including Amnion-derived Cellular Cytokine Solution (referred to herein as ACCS) obtained from culturing Amnion-derived Multipotent Progenitor (AMP) cells, dispersed in a polymeric coating material.
Claims20
An improved implantable medical device useful for surgical implantation into a subject's body, wherein the improvement to the implantable medical device comprises an implantable medical device having a coating on its surface, wherein the coating comprises Cellular Factor-containing Solution (CFS) compositions dispersed in a polymeric coating material.
An improved insertable medical device useful for surgical insertion into a subject's body, wherein the improvement to the insertable medical device comprises an insertable medical device having a coating on its surface, wherein the coating comprises Cellular Factor-containing Solution (CFS) compositions dispersed in a polymeric coating material.
An improved transcutaneous medical device useful for insertion into a subject's body, wherein the improvement to the transcutaneous medical device comprises a transcutaneous medical device having a coating on its surface, wherein the coating comprises Cellular Factor-containing Solution (CFS) compositions dispersed in a polymeric coating material.
A method for down-regulating the inflammatory response that occurs following the implantation, insertion or transcutaneous placement of a medical device in a patient, the method comprising the step of coating the medical device with a composition comprising Cellular Factor-containing Solution (CFS) compositions dispersed in a polymeric coating material.
Dependencies are inferred from the claim text.