Use of calcitonin in osteoarthritis
AssigneeNovartis AG
InventorsMoise Azria, Claus Christiansen, Simon David Bateman, Shoufeng Li
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Abstract
The present invention relates to a novel use of calcitonin in osteoarthritis, and to methods of treating and/or preventing osteoarthritis in mammals, particularly humans.
Claims13
A method of preventing or/and treating osteoarthritis in a patient in need thereof comprising administering to said patient a therapeutically effective amount of a calcitonin in free or salt form.
A method of inhibiting resorption and/or normalizing turnover of subchondral bone in a patient in need thereof comprising administering to said patient a therapeutically effective amount of a calcitonin in free or salt form.
A pharmaceutical composition for use in the treatment or/and prevention of osteoarthritis in a patient in need thereof, comprising a calcitonin together with one or more pharmaceutically acceptable diluents or carriers therefore.
A pharmaceutical combination for use in the treatment or/and prevention of osteoarthritis in a patient in need thereof, comprising:
- a) a first agent which is a calcitonin, and
- b) a co-agent which is a bone resorption inhibitor, bone forming drug or pain reducing agent.
Dependencies are inferred from the claim text.