Use of lxr antagonists for treatment of side effects of elevated glucocorticoid levels
AssigneesArturo Orellana, The Governing Council of the University of Toronto, Fernando A. Fernandez
InventorsCarolyn Cummins, Arturo Orellana, Rucha Patel, Fernando A. Fernandez
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Abstract
The present application is directed to uses of an agent that antagonizes the LXRβ receptor for the treatment of side effects associated with elevated glucocorticoid levels as well as uses of a glucocorticoid in combination with the agent that antagonizes the LXRβ receptor for treatment of a disease wherein glucocorticoid treatment is indicated.
Claims18
A method of treating a side effect of elevated glucocorticoid levels comprising administering a therapeutically effective amount of an agent that antagonizes the LXRβ receptor to a subject in need thereof.
A compound of the formula:
- or a pharmaceutically acceptable solvate thereof.
Dependencies are inferred from the claim text.