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US 2014/0271648 A1Published application
Interferon Alpha and Omega Antibody Antagonists
AssigneeJanssen Biotech, Inc.
InventorsEllen Chi, Judith Connor, Chichi Huang, Jarrat Jordan, Xiefan Lin-Schmidt, Jinquan Luo, Lu Lu, Christian Martinez, Galina Obmolova, Ronald Swanson
Life of this patent
Estimating the term…
Abstract
Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of diseases associated with increased production of IFNα and IFNω.
Claims45
An isolated monoclonal antibody that binds to and neutralizes an activity of (a) human interferon omega (IFNω) and (b) at least four, five, six, seven, eight, nine or ten human interferon alpha (IFNα) subtypes.
Dependencies are inferred from the claim text.