Treatment Method and Product for Uterine Fibroids using Purified Collagenase
AssigneesDuke University, BioSpecifics Technologies Corp.
InventorsPhyllis Carolyn Leppert, Thomas L. Wegman
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Abstract
The invention relates to compositions and methods for treating uterine fibroids, wherein a uterine fibroid treatment agent comprising collagenase in an amount effective to cause shrinkage of uterine fibroids is injected or inserted into the uterine fibroid.
Claims38
A method for the treatment of uterine fibroids, said method comprising:
- providing an injectable or insertable formulation that comprises a uterine fibroid treatment agent in an amount effective to cause shrinkage of uterine fibroids;
- and injecting or inserting said formulation into the uterine fibroid, wherein the uterine fibroid treatment agent is collagenase.
A system for the treatment of uterine fibroids, said system comprising:
- (a) an injectable or insertable formulation that comprises a uterine fibroid treatment agent in an amount effective to cause shrinkage of uterine fibroids;
- and (b) an apparatus for injecting or inserting said formulation into said fibroids, wherein the uterine fibroid treatment agent is collagenase.
A fibroid injectable or insertable formulation that comprises collagenase and one or more of a non-steroidal anti-inflammatory drug, an oral contraceptive, a GnRH agonist, an antiprogestogen, and a selective progesterone receptor modulator, in an amount effective to cause shrinkage of uterine fibroids.
Dependencies are inferred from the claim text.