Formulations of water-soluble derivatives of vitamin e and compositions containing same
AssigneeVirun, Inc.
InventorPhilip J. Bromley
Life of this patent
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Abstract
Provided are compositions that contain water-soluble vitamin E derivative mixtures (compositions), such as tocopheryl polyethylene glycol succinate (TPGS), TPGS analogs, TPGS homologs and TPGS derivatives. The water-soluble vitamin E mixtures contain mixtures that include dimers and monomers of the vitamin E derivative, where the amount of dimer is greater than 12%, such as 29%, 35%, 50%, 60%, and the amount of monomer is less than 87% by weight of the water-soluble vitamin E derivative mixture. Also provided are products containing the water-soluble vitamin E derivative mixtures, including, concentrates for dilution into aqueous beverages and compositions for direct ingestion.
Claims47
A composition, comprising:
- a water-soluble vitamin E derivative mixture present in an amount of from between 1% to 99%, inclusive, by weight of the composition, wherein the water-soluble vitamin E derivative mixture comprises at least 13 wt % water-soluble vitamin E derivative dimer and up to 87% vitamin E derivative monomer;
- and
- a non-polar compound other than the water-soluble vitamin E derivative mixture and mixtures of the non-polar compounds.
A composition consisting essentially of:
- a water-soluble vitamin E derivative mixture present in an amount of from between 5% and 95% by weight of the composition, wherein the water-soluble vitamin E derivative mixture comprises from between 25 wt % and 69 wt % water-soluble vitamin E monomer and from between 13 wt % and 75 wt % water-soluble vitamin E dimer;
- a non-polar compound other than the water-soluble vitamin E derivative mixture, present in an amount of from between 1% and 75% by weight of the composition;
- and
- a preservative present in an amount sufficient to preserve the composition.
A composition, consisting essentially of:
- a water-soluble vitamin E derivative mixture present in an amount of from between 5% and 95% by weight of the composition, wherein:
- the water-soluble vitamin E derivative mixture comprises from between 25 wt % and 69 wt % water-soluble vitamin E monomer and from between 13 wt % and 75 wt % water-soluble vitamin E dimer;
- a non-polar compound other than the water-soluble vitamin E derivative mixture, present in an amount of from between 1% and 75% by weight of the composition;
- a preservative present in an amount sufficient to preserve the composition;
- and
- a non-polar solvent that differs from the non-polar compound and is present in an amount at least sufficient to dissolve the non-polar compound.
A composition for direct consumption, comprising in an aqueous beverage base, either:
- (a) a non-polar ingredient in an amount between at or about 0.001% and at or about 0.1% by weight;
- and
- (b) a water-soluble vitamin E derivative mixture in an amount between at or about 0.1% and at or about 5% by weight, or 0.1% and 15% by weight of the composition.
Dependencies are inferred from the claim text.