Expiration Indication Label

A time indicating label for attachment to a tube, the label comprising:

• (A) An impermeable facesheet having first and second facial surfaces, the first facial surface adapted to accepting a graphic before or after attachment of the label to a tube,
• (B) An activation layer comprising a polymer matrix and an activating agent, the activation layer having first and second facial surfaces, the first facial surface of the activation layer in contact with the second facial surface of the facesheet,
• (C) A barrier tape impermeable to the activating agent of the activation layer, the barrier tape having first and second facial surfaces, the first facial surface of the barrier tape in partial contact with the activation layer,
• (D) An impermeable release liner having first and second facial surfaces, the first facial surface of the release liner in contact with that part of the second facial surface of the activation layer not in contact with the first facial surface of the barrier tape,
• (E) A timing layer comprising a film-forming polymer resin and a pigment, the timing layer having first and second facial surfaces, the first facial surface of the timing layer in contact with the second facial surface of the barrier tape and the second facial surface of the release liner,
• (F) A dye layer comprising a film-forming polymer resin and an organic dye soluble in the activating agent, the dye layer having first and second facial surfaces, the first facial surface of the dye layer in contact with the second facial surface of the timing layer, and
• (G) A base layer comprising a substrate impermeable to the dye of the dye layer and the activating agent of the activation layer, the base layer having first and second facial surfaces, the first facial surface of the base layer in contact with the second facial surface of the dye layer;
• with the provisos that the:
• (1) Part of the base layer extending beyond the barrier tape and activating layer comprises at least one aperture sized to accept a tube of a pre-determined diameter,
• (2) Release liner can be removed from the activation layer with less than 20 grams per inch width (g/in width) of force,
• (3) Release liner film has stiffness as measured by Taber stiffness greater than the facesheet;
• and
• (4) The timing layer, the dye layer and base layer comprise a bottom sheet component of the label, the bottom sheet having a Taber stiffness of greater than 0.1.