Patient-specific automated tuning of boundary conditions for distal vessel tree
AssigneeSiemens Aktiengesellschaft
InventorsLucian Mihai Itu, Puneet Sharma, Ali Kamen, Dorin Comaniciu
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Abstract
Boundary conditions for a distal vessel tree are modeled and tuned to a specific patient. Measurements from the patient are used to find reference compliance and resistance for the root of the distal vessel tree model. The reference compliance and resistance are used to tune properties of a structured tree model, such as by iteratively solving for the properties while matching the compliance and resistance of the structured tree model to the patient-specific reference compliance and reference resistance. The tuned structured tree is then used to calculate boundary conditions for computing flow of a scanned vessel of the patient.
Claims20
A method for automated tuning of boundary conditions for a distal vessel tree, the method comprising:
- acquiring scan data representing a vessel of a patient and one or more outlets of the vessel;
- modeling a distal vessel tree structure;
- tuning the modeling as a function of a match with one or more characteristics of the patient;
- determining, from the tuning, one or more boundary conditions for the respective one or more outlets based on a relationship between flow and pressure;
- computing a blood flow quantity for the vessel of the patient as a function of the boundary conditions;
- and
- displaying the blood flow quantity.
In a non-transitory computer readable storage medium having stored therein data representing instructions executable by a programmed processor for automated tuning of boundary conditions for a distal vessel tree, the storage medium comprising instructions for:
- generating a structured tree model with compliance and resistance values set to values obtained from a patient;
- calculating boundary conditions from the structured tree model, the boundary conditions calculated from characteristics of the structured tree model responsive to the compliance and resistance values;
- and
- determining a hemodynamic property of a vessel of the patient as a function of the boundary conditions.
A system for automated tuning of boundary conditions for a distal vessel tree, the system comprising:
- a scanner configured to scan a vessel of a patient;
- and
- a processor configured to determine boundary condition of the vessel from a structured tree construct, to determine first characteristics of the structured tree construct from a match of one or more second characteristics of the structured tree construct with values specific to the patient, and to determine a flow characteristic of the vessel with the boundary condition.
Dependencies are inferred from the claim text.