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US 2014/0236286 A1Published application
Drug delivery system and method of manufacturing thereof
OwnerSean R. Kirkpatrick, Richard C. Svrlugainventors
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OwnerSean R. Kirkpatrick, Richard C. Svrlugainventors
Estimating the term…
A medical device for surgical implantation adapted to serve as a drug delivery system has one or more drug loaded holes with barrier layers to control release or elution of the drug from the holes or to control inward diffusion of fluids into the holes. The barrier layers are non-polymers and are formed from the drug material itself by beam processing. The holes may be in patterns to spatially control drug delivery. Flexible options permit combinations of drugs, variable drug dose per hole, multiple drugs per hole, temporal control of drug release sequence and profile. Methods for forming such a drug delivery system are also disclosed. Gas cluster ion beam and/or accelerated Neutral Beam derived from an accelerated gas cluster ion beam may be employed.
A method of modifying a surface of a medical device comprising the steps:
A drug eluting medical device having a region with one or more drug coating layer(s), wherein at least one of the drug coating layer(s) comprises a barrier layer formed from Neutral Beam irradiated drug, and wherein the barrier layer is adapted to control a rate of flow of material across the barrier.
Dependencies are inferred from the claim text.