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US 2014/0235832 A1Published application
Rank ligand polypeptides
AssigneeImmunex Corporation
InventorDirk M. ANDERSON
Life of this patent
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Abstract
Described herein are kits for use in detecting RANKL polypeptides.
Claims8
A kit for detecting RANKL protein, said kit comprising a RANKL polypeptide selected from the group consisting of:
- a) a polypeptide comprising amino acids 1-317 of SEQ ID NO:13;
- b) a polypeptide comprising amino acids 69-313 of SEQ ID NO:13;
- c) a polypeptide comprising amino acids 162-313 of SEQ ID NO:13
- d) a polypeptide comprising amino acids 138-317 of SEQ ID NO:13;
- e) a polypeptide comprising amino acids x to y of SEQ ID NO:13, wherein x is an amino terminal amino acid between 69 and 162 of SEQ ID NO:13, and y is a carboxy terminal amino acid between 313 and 317 of SEQ ID NO:13;
- and
- f) a polypeptide having an at least 90% amino acid sequence identity with a polypeptide comprising amino acids 162-317 of SEQ ID NO:13.
4 more elements
A kit for detecting the presence of human RANKL nucleic acid in an in vitro assay, said kit comprising at least one fragment of DNA that comprises at least 17 nucleotides of SEQ ID NO:12 or that comprises at least 17 nucleotides complementary to SEQ ID NO:12.
Dependencies are inferred from the claim text.