Thiophene compounds
AssigneeVertex Pharmaceuticals Incorporated
InventorBrian Luisi
Life of this patent
Estimating the term…
Abstract
A co-crystal of Compound (1) includes Compound (1) and a co-crystal former selected from the group consisting of urea, nicotinamide, and isonicotinamide, wherein Compound (1) is characterized by the following structural formula: A pharmaceutical composition includes such a co-crystal of Compound (1) and at least one pharmaceutically acceptable carrier or excipient.
Claims38
A co-crystal comprising Compound (1) and a co-crystal former selected from the group consisting of urea, nicotinamide, and isonicotinamide, wherein Compound (1) is represented by the following structural formula:
A method of preparing a co-crystal comprising Compound (1) and a co-crystal former selected from the group consisting of urea, nicotinamide, isonicotinamide, wherein Compound (1) is represented by the following structural formula:
- comprising the step of:
- stirring a mixture of Compound 1 and the co-crystal former to form the co-crystal.
Dependencies are inferred from the claim text.