Inhibition of microrna-134 for the treatment of seizure-related disorders and neurologic injuries
OwnerDavid Henshall, Eva Jimenez-Mateosinventors
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Abstract
A method for preventing or treating epilepsy or status epilepticus, or a brain-related disorder characterised by precipitation of seizures, in an individual, the method comprising the step of treating the individual with an agent capable of inhibiting the activity of miR-134 in the individual, wherein the agent is delivered to the brain of the individual.
Claims21
1-25. (canceled)
A method for treating epilepsy or status epilepticus in an individual comprising administering an agent for inhibiting the activity of miR-134 to the individual, wherein the agent is delivered to the brain of the individual.
A method for inhibiting the development or reducing occurrence of seizures in an individual having a brain-related disorder characterized by development of seizures comprising administering an agent for inhibiting the activity of miR-134 to the individual, wherein the agent is delivered to the brain of the individual.
A method for treating acute neurological injury likely to cause brain damage in an individual comprising administering to the individual an agent for inhibiting the activity of miR-134.
Dependencies are inferred from the claim text.