Back to results
US 2014/0235657 A1Published application
Therapeutic compounds and uses thereof
AssigneeKala Pharmaceuticals, Inc.
InventorsWinston Zapanta ONG, Pawel Wojciech Nowak, Ben C. Askew, Jinsoo Kim
Life of this patent
Estimating the term…
Abstract
Described herein are compounds of Formula (I)-(III), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also provided are particles (e.g., nanoparticles) comprising compounds of Formula (I)-(III) and pharmaceutical compositions thereof that are mucus penetrating. Methods of using the compounds or pharmaceutical compositions thereof for treating and/or preventing diseases are also provided.
Claims38
A compound of Formula (I):
- or a pharmaceutically acceptable salt thereof, wherein:
- R1 is hydrogen or optionally substituted C1-6 alkyl;
- R2 is optionally substituted heterocyclyl;
- X is a bond, —O—, or —C(═O)—;
- Y is CH or N;
- R3 is optionally substituted heteroaryl;
- and
- n is 0, 1, 2, 3, or 4.
5 more elements
-51. (canceled)
Dependencies are inferred from the claim text.