Pyridine Compounds and Uses Thereof

A compound of Formula I:

• wherein each X1, X2, X3 and X4 is independently N or CR3 provided one X is N and the remaining X are each independently CR3;
• wherein R1 is C1-C6 alkyl, C3-C6 cycloalkyl, tetrahydropyranyl, benzyl, phenyl and pyridyl, in which the benzyl, phenyl and pyridyl is optionally substituted with one or more halogen, CN, C1-C4 alkyl/fluoroalkyl or C1-C4 alkoxy/fluoroalkoxy;
• wherein R2 is C1-C4 alkyl or C3-C6 cycloalkyl;
• and
• wherein R3 is hydrogen, halogen, CN, —CO2H, —CON(H or C1-C4 alkyl)2, CHO, C1-C4 alkyl/fluoroalkyl, a cyclic amino containing heterocycle, C2-C4 alkenyl, C2-C4 alkenyl or C1-C4 alkoxy/fluoroalkoxy;
• or a pharmaceutically acceptable salt thereof.