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US 2014/0235599 A1Published application
Combination of pilocarpin and methimazol for treating charcot-marietooth disease and related disorders
AssigneePharnext
InventorsDANIEL COHEN, ILYA CHUMAKOV, SERGUEI NABIROCHKIN, OXANA GUERASSIMENKO
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Abstract
The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related peripheral neuropathies. More particularly, the invention relates to combined therapies for treating said disease by affecting simultaneously muscarinic receptor signalling and thyroid hormone pathway in a subject.
Claims10
(canceled)
A method of treating toxic neuropathy in a subject in need thereof comprising the administration to said subject of a combination product or composition comprising:
- a) pilocarpine or a salt thereof;
- b) methimazole, carbamizole or a salt thereof;
- and
- c) a pharmaceutically acceptable carrier or excipient.
1 more element
Dependencies are inferred from the claim text.