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US 2014/0235453 A1Published application
Global transcription machinery engineering
AssigneeMassachusetts Institute of Technology
InventorsHal S. Alper, Gregory Stephanopoulos
Life of this patent
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Abstract
The invention relates to global transcription machinery engineering to produce altered cells having improved phenotypes.
Claims35
A method for altering the phenotype of a cell comprising:
- mutating a nucleic acid encoding global transcription machinery and, optionally, its promoter,
- expressing the nucleic acid in a cell to provide an altered cell that includes mutated global transcription machinery, and
- culturing the altered cell.
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Dependencies are inferred from the claim text.