Green Process for Producing Polyhydroxyalkanoates and Chemicals Using a Renewable Feedstock
AssigneeMetabolix, Inc.
InventorsZhigang Zhang, Christopher W.J. McChalicher, Johan van Walsem, Oliver P. Peoples, Richard P. Eno, Thomas Martin Ramseier
Life of this patent
Estimating the term…
Abstract
Disclosed are organisms genetically engineered to make useful products when grown on ethanol as a carbon source. The organisms are genetically engineered to produce various useful products such as polyhydroxyalkanoates, diols, diacids, higher alcohols, and other useful chemicals.
Claims14
An organism homologously capable of converting ethanol to acetyl-CoA when grown on ethanol as a carbon source, wherein the organism is genetically engineered to produce a polyhydroxyalkanoate polymer.
An organism homologously capable of producing a polyhydroxyalkanoate polymer, wherein the organism is genetically engineered to convert ethanol to acetyl-CoA when grown on ethanol as a carbon source.
An organism that is genetically engineered to convert ethanol to acetyl-CoA when grown on ethanol as a carbon source, and genetically engineered to produce a polyhydroxyalkanoate polymer.
8-28. (canceled)
30-92. (canceled)
The organism of 3, wherein the organism is selected from the group consisting of:
- Escherichia coli, Ralstonia eutropha, Acinetobacter baumannii, Acinetobacter baylyi, Acinetobacter aceti, Acinetobacter sp. DRI, Acinetobacter calcoaceticus, Acinetobacter haemolyticus, Acinetobacter johnsonii, Acinetobacter junii, Acinetobacter lwoffii, Acinetobacter radioresistens, Acinetobacter venetianus, Acinetobacter sp. DSM, Zoogloea ramigera, Allochromatium vinosum, Rhodococcus ruber, Delftia acidovorans, Aeromonas caviae, Synechocystis sp. PCC 6803, Synechococcus elongates PCC 7942, Thiocapsa pfenigii, Bacillus megaterium, Clostridium kluyveri, Methylobacterium extorquens, Nocardia corral ina, Nocardia salmonicolor, Pseudomonas fluorescens, Pseudomonas oleovorans, Pseudomonas sp. 6-19, Pseudomonas sp. 61-3 and Pseudomonas putida, Rhodobacter sphaeroides, Alcaligenes latus, Klebsiella oxytoca, Anaerobiospirillum succiniciproducens, Actinobacillus succinogenes, Mannheimia succiniciproducens, Rhizobium etli, Bacillus subtilis, Corynebacterium glutamicum, Gluconobacter oxydans, Zymomonas mobilis, Lactococcus lactis, Lactobacillus plantarum, Streptomyces coelicolor, Clostridium acetobutylicum, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Kiuyveromyces iactis, Kiuyveromyces marxianus, Aspergillus terreus, Aspergillus niger, Pichia pastoris, Chiarella spp., Chiarella minutissima, Chiarella emersonii, Chiarella sorokiniana, Chiarella ellipsoidea, Chiarella sp., and Chiarella protothecoides.
The organism of 5, wherein the organism is selected from the group consisting of:
- Escherichia coli, Ralstonia eutropha, Acinetobacter baumannii, Acinetobacter baylyi, Acinetobacter aceti, Acinetobacter sp. DRI, Acinetobacter calcoaceticus, Acinetobacter haemolyticus, Acinetobacter johnsonii, Acinetobacter junii, Acinetobacter lwoffii, Acinetobacter radioresistens, Acinetobacter venetianus, Acinetobacter sp. DSM, Zoogloea ramigera, Allochromatium vinosum, Rhodococcus ruber, Delftia acidovorans, Aeromonas caviae, Synechocystis sp. PCC 6803, Synechococcus elongatus PCC 7942, Thiocapsa pfenigii, Bacillus megaterium, Clostridium kluyveri, Methylobacterium extorquens, Nocardia corral ina, Nocardia salmonicolor, Pseudomonas fluorescens, Pseudomonas oleovorans, Pseudomonas sp. 6-19, Pseudomonas sp. 61-3 and Pseudomonas putida, Rhodobacter sphaeroides, Alcaligenes latus, Klebsiella oxytoca, Anaerobiospirillum succiniciproducens, Actinobacillus succinogenes, Mannheimia succiniciproducens, Rhizobium etli, Bacillus subtilis, Corynebacterium glutamicum, Gluconobacter oxydans, Zymomonas mobilis, Lactococcus lactis, Lactobacillus plantarum, Streptomyces coelicolor, Clostridium acetobutylicum, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Kiuyveromyces iactis, Kiuyveromyces marxianus, Aspergillus terreus, Aspergillus niger, Pichia pastoris, Chiarella spp., Chiarella minutissima, Chiarella emersonii, Chiarella sorokiniana, Chiarella ellipsoidea, Chiarella sp., and Chiarella protothecoides.
Dependencies are inferred from the claim text.