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US 2014/0234941 A1Published application
Phosphatidic acid phosphatase gene
AssigneeSuntory Holdings Limited
InventorMisa Ochiai
Life of this patent
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Abstract
The present invention provides a novel phosphatidic acid phosphatase gene. The object of the present invention can be solved by providing a nucleic acid comprising the nucleotide sequence set forth in SEQ ID NO: 1, SEQ ID NO: 4, or SEQ ID NO: 5; a protein comprising the amino acid sequence set forth in SEQ ID NO: 2; and mutants thereof.
Claims15
A nucleic acid according to any one of (a) to (g) below:
- (a) a nucleic acid comprising a nucleotide sequence encoding a protein that consists of an amino acid sequence with deletion, substitution, or addition of one or more amino acids in the amino acid sequence set forth in SEQ ID NO:
- 2 and that has a phosphatidic acid phosphatase activity;
- (b) a nucleic acid comprising a nucleotide sequence that is hybridizable under stringent conditions with a nucleic acid consisting of a nucleotide sequence complementary to the nucleotide sequence set forth in SEQ ID NO:
- 1 and that encodes a protein having a phosphatidic acid phosphatase activity;
- (c) a nucleic acid comprising a nucleotide sequence that has an identity of 70% or more with the nucleotide sequence set forth in SEQ ID NO:
- 1 and that encodes a protein having a phosphatidic acid phosphatase activity;
- (d) a nucleic acid comprising a nucleotide sequence encoding a protein that consists of an amino acid sequence having an identity of 70% or more with the amino acid sequence set forth in SEQ ID NO:
- 2 and that has a phosphatidic acid phosphatase activity;
- (e) a nucleic acid comprising a nucleotide sequence that is hybridizable under stringent conditions with a nucleic acid consisting of a nucleotide sequence complementary to a nucleotide sequence encoding a protein consisting of the amino acid sequence set forth in SEQ ID NO:
- 2 and that encodes a protein having a phosphatidic acid phosphatase activity;
- (f) a nucleic acid comprising a nucleotide sequence that is hybridizable under stringent conditions with a nucleic acid consisting of a nucleotide sequence complementary to the nucleotide sequence set forth in SEQ ID NO:
- 4 and that includes an exon encoding a protein having a phosphatidic acid phosphatase activity;
- and
- (g) a nucleic acid comprising a nucleotide sequence that has an identity of 70% or more with the nucleotide sequence set forth in SEQ ID NO:
- 4 and that includes an exon encoding a protein having a phosphatidic acid phosphatase activity.
12 more elements
A nucleic acid according to any one of (a) to (g) below:
- (a) a nucleic acid comprising a nucleotide sequence encoding a protein that consists of an amino acid sequence with deletion, substitution, or addition of 1 to 110 amino acids in the amino acid sequence set forth in SEQ ID NO:
- 2 and that has a phosphatidic acid phosphatase activity;
- (b) a nucleic acid comprising a nucleotide sequence that is hybridizable under conditions of 2×SSC at 50° C. with a nucleic acid consisting of a nucleotide sequence complementary to the nucleotide sequence set forth in SEQ ID NO:
- 1 and that encodes a protein having a phosphatidic acid phosphatase activity;
- (c) a nucleic acid comprising a nucleotide sequence that has an identity of 90% or more with the nucleotide sequence set forth in SEQ ID NO:
- 1 and that encodes a protein having a phosphatidic acid phosphatase activity;
- (d) a nucleic acid comprising a nucleotide sequence encoding a protein that consists of an amino acid sequence having an identity of 90% or more with the amino acid sequence set forth in SEQ ID NO:
- 2 and that has a phosphatidic acid phosphatase activity;
- (e) a nucleic acid comprising a nucleotide sequence that is hybridizable under conditions of 2×SSC at 50° C. with a nucleic acid consisting of a nucleotide sequence complementary to a nucleotide sequence encoding a protein consisting of the amino acid sequence set forth in SEQ ID NO:
- 2 and that encodes a protein having a phosphatidic acid phosphatase activity;
- (f) a nucleic acid comprising a nucleotide sequence that is hybridizable under conditions of 2×SSC at 50° C. with a nucleic acid consisting of a nucleotide sequence complementary to the nucleotide sequence set forth in SEQ ID NO:
- 4 and that includes an exon encoding a protein having a phosphatidic acid phosphatase activity;
- and
- (g) a nucleic acid comprising a nucleotide sequence that has an identity of 90% or more with the nucleotide sequence set forth in SEQ ID NO:
- 4 and that includes an exon encoding a protein having a phosphatidic acid phosphatase activity.
12 more elements
A nucleic acid according to any one of (a) to (d) below:
- (a) a nucleic acid comprising the nucleotide sequence set forth in SEQ ID NO:
- 1 or a fragment thereof;
- (b) a nucleic acid comprising a nucleotide sequence encoding a protein consisting of the amino acid sequence set forth in SEQ ID NO:
- 2 or a fragment thereof;
- (c) a nucleic acid comprising the nucleotide sequence set forth in SEQ ID NO:
- 4 or a fragment thereof;
- and
- (d) a nucleic acid comprising the nucleotide sequence set forth in SEQ ID NO:
- 5 or a fragment thereof.
6 more elements
A protein according to (a) or (b) below:
- (a) a protein comprising an amino acid sequence with deletion, substitution, or addition of one or more amino acids in the amino acid sequence set forth in SEQ ID NO:
- 2 and having a phosphatidic acid phosphatase activity;
- and
- (b) a protein comprising an amino acid sequence having an identity of 70% or more with the amino acid sequence set forth in SEQ ID NO:
- 2 and having a phosphatidic acid phosphatase activity.
2 more elements
A protein according to (a) or (b) below:
- (a) a protein comprising an amino acid sequence with deletion, substitution, or addition of 1 to 110 amino acids in the amino acid sequence set forth in SEQ ID NO:
- 2 and having a phosphatidic acid phosphatase activity;
- and
- (b) a protein comprising an amino acid sequence having an identity of 90% or more with the amino acid sequence set forth in SEQ ID NO:
- 2 and having a phosphatidic acid phosphatase activity.
2 more elements
A protein comprising the amino acid sequence set forth in SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.