Method And System For Detection Of Natural High Intensity Sweeteners That Contain Hydroxyl Groups
AssigneePureCircle Sdn Bhd
InventorsJose Antonio Gabaldon Hernandez, Estrella Nunez Delicado, Rosa Puchades Pla, Angel Maquiera, Eva Maria Brun Sanchez, Avetik Markosyan
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Abstract
The present invention provides a hapten derivative and conjugate of a natural high intensity sweetener containing hydroxyl groups. The conjugate can be used to produce antibodies specific against the natural high intensity sweetener. The present invention further provides a kit and method for detecting and quantifying the natural high intensity sweetener in a sample.
Claims25
A hapten derivative of a natural high intensity sweetener containing hydroxyl groups, said hapten derivative has the structure selected from the group consisting of:
- wherein the hapten derivative is used for further making conjugates for being used as an immunogen for generating antibodies specific for the natural high intensity sweetener or a reagent for detecting the natural high intensity sweetener.
A conjugate of a natural high intensity sweetener containing hydroxyl groups, said conjugate has the structure of formula (1) and (2):
- wherein X is a linker chain comprising 1-8 carbon or hetero atoms;
- Y is selected from the group consisting of —CO, —NH2, and NCO—;
- and Z is an antigenic carrier or a label;
- and wherein the conjugate is used as an immunogen for generating antibodies specific for the natural high intensity sweetener or a reagent for detecting the natural high intensity sweetener.
Dependencies are inferred from the claim text.