Magnetic removal or identification of damaged or compromised cells or cellular structures
AssigneeInguran, LLC
InventorKristie Marie Krug
Life of this patent
Estimating the term…
Abstract
A method for magnetic cellular manipulation may include contacting a composition with a biological sample to form a mixture. The composition may include a plurality of particles. Each particle in the plurality of particles may include a magnetic substrate. The magnetic substrate may be characterized by a magnetic susceptibility greater than zero. The composition may also include a chargeable silicon-containing compound. The chargeable silicon-containing compound may coat at least a portion of the magnetic substrate. The biological sample may include cells and/or cellular structures. The method may also include applying a magnetic field to the mixture to manipulate the composition.
Claims20
A composition for magnetic cellular manipulation, the composition comprising a plurality of particles, each particle in the plurality of particles comprising:
- a magnetic substrate, the magnetic substrate characterized by a magnetic susceptibility greater than zero;
- and
- a chargeable silicon-containing compound, the chargeable silicon-containing compound coating at least a portion of the magnetic substrate.
A method for magnetic cellular manipulation, the method comprising:
- contacting a composition with a biological sample to form a mixture, the composition comprising a plurality of particles, each particle in the plurality of particles comprising:
- a magnetic substrate, the magnetic substrate characterized by a magnetic susceptibility greater than zero;
- and
- a chargeable silicon-containing compound, the chargeable silicon-containing compound coating at least a portion of the magnetic substrate;
- and
- the biological sample comprising cells and/or cellular structures;
- and
- applying a magnetic field to the mixture to manipulate the composition.
A kit for magnetic cellular manipulation, the kit comprising:
- instructions, the instructions comprising:
- contacting a composition with a biological sample to form a mixture;
- applying a magnetic field to the mixture to manipulate the composition;
- the composition, the composition comprising a plurality of particles, each particle in the plurality of particles comprising:
- a magnetic substrate, the magnetic substrate characterized by a magnetic susceptibility greater than zero;
- and
- a chargeable silicon-containing compound, the chargeable silicon-containing compound coating at least a portion of the magnetic substrate.
Dependencies are inferred from the claim text.