Composition comprising an extract of combined herbs consisting of ginseng and Vitis genus plant for preventing and treating Neuro-degenerative disease and enhancing memory power
AssigneeGinseng Science Inc.
InventorsBok Deuk Kim, Jeong Hill Park, Jonghoon Ryu
Life of this patent
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Abstract
The present invention relates to compositions comprising an extract of combined herbs consisting of ginseng and Vitis genus plant for treating and preventing neuro-degenerative disease and enhancing memory power. The combined inventive extract showed synergistic enhancing effect through passive avoidance test using by scopolamine-induced memory injured animal model comparing with respective extract, therefore the inventive extract can be useful in treating or preventing neuro-degenerative disease.
Claims16
A pharmaceutical composition comprising an extract of combined herbs consisting of ginseng and Vitis genus plant for treating and preventing neuro-degenerative disease and enhancing memory power.
(canceled)
A method for treating neuro-degenerative disease in a mammal or animal suffering from said disease comprising administering an effective amount of an extract of combined herbs consisting of ginseng and Vitis genus plant, together with a pharmaceutically acceptable carrier to said mammal or animal in need thereof
A health functional food comprising an extract of combined herbs consisting of ginseng and Vitis genus plant as an active ingredient for alleviating or preventing neuro-degenerative disease and enhancing memory power.
A health care food comprising an extract of combined herbs consisting of ginseng and Vitis genus plant for alleviating or preventing neuro-degenerative disease and enhancing memory power, together with a sitologically acceptable additive.
(canceled)
A method for preparing extract of combined herbs consisting of ginseng and Vitis genus plant comprising the steps of;
- drying the fruit, seed, root, leaf or stem of ginseng and Vitis genus plant and heating the ginseng with high temperature ranging from 70 to 200° C. for the period ranging from 0.5 to 20 hours so as to make a ratio of ginsenoside (Rg3+Rg5+Rk1) to (Rb1+Rb2+Rc+Rd) of over 1.0 at 1st step;
- mixing the plant materials with 1 to 50-fold weight (w/v) of water, C1-C4 lower alcohol or the mixture thereof and extracting the solution by reflux extraction, cold water extraction, ultra-sonication or other conventional extraction at the temperature ranging from 10 to 150° C. for the period ranging from 0.5 to 20 hours;
- filtering the residue or precipitating the suspended solution prepared by adding water with cold ethanol to afford their supernatant at 2nd step;
- drying the filtrate or the supernatant at the temperature ranging from 40 to 80° C.;
- mixing each dried extract with the mixed ratio based on the dried weight of each herb (w/w) ranging from 1:0.01-1000.
Dependencies are inferred from the claim text.