Topical Composition for Stimulating Epidermis and Dermis Layers of the Skin
OwnerNicholas V. Perricone, Peter T. Puglieseinventors
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Abstract
The invention provides topical compositions including vitamin A, colostrum (or extracts of colostrum with a high IGF content) with or without avian eggshell membrane, that stimulate the epidermis and dermis layers of the skin to treat skin aging.
Claims30
A topical composition comprising:
- an effective amount of vitamin A;
- an effective amount of at least one compound selected from the group consisting of:
- insulin like growth factors (“IGF”), colostrum, IGF extracted from colostrum, a peptide extract of colostrum which is rich IGF, and avian eggshell membrane;
- and
- a dermatologically acceptable carrier.
A topical composition comprising:
- about 0.01% to about 0.5% by weight vitamin A;
- about 0.05% to about 2.0% by weight avian eggshell membrane or at least one component of eggshell membrane;
- and
- a dermatologically acceptable carrier.
A topical composition comprising:
- about 0.1% by weight retinol;
- about 0.35% to 0.7% by weight of at least one of peptide extract of colostrum which is rich in insulin like growth factor and optionally eggshell membrane;
- and
- a dermatologically acceptable carrier comprising phosphatidylcholine.
A method for preparing a topical composition having a water phase, an oil phase, an aqueous DMAE mixture, vitamin A, one or more of eggshell membrane and colostrum or extracts thereof, and preservative agent, comprising the steps of:
- adding the water phase to the oil phase;
- mixing the water phase with the oil phase;
- cooling to about 58° C.;
- adding the preservative agent;
- cooling to about 30° C.;
- adding the vitamin A;
- cooling to about 28° C.;
- adding the one more component of eggshell membrane and colostrum;
- homogenizing;
- adding the DMAE mixture;
- and
- overlaying the resulting mixture with nitrogen.
A method for treatment of aging skin, comprising administering to the skin a composition comprising:
- an effective amount of vitamin A;
- an effective amount of at least one compound selected from the group consisting of:
- insulin like growth factors (“IGF”), colostrum, IGF extracted from colostrum, a peptide extract of colostrum which is rich IGF, and avian eggshell membrane;
- and
- a dermatologically acceptable carrier.
A method for stimulating epidermis and dermis layers of the skin, comprising administering to the skin the composition comprising:
- an effective amount of vitamin A;
- an effective amount of at least one compound selected from the group consisting of:
- insulin like growth factors (“IGF”), colostrum, IGF extracted from colostrum, a peptide extract of colostrum which is rich IGF, and avian eggshell membrane;
- and
- a dermatologically acceptable carrier.
Dependencies are inferred from the claim text.