Influenza vaccine
AssigneeThe United States of America, as represented by the Secretary, Dept.of Health and Human Services
InventorsJoanna Kubler-Kielb, Jerry Keith, Rachel Schneerson, Zuzana Biesova
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Abstract
Disclosed are immunogenic conjugates having the general formula: HA2-XXX-Pr, where HA2 is the influenza HA2 fusion peptide or a portion thereof, XXX is a linker and Pr is the carrier. Methods of producing an immune response in a subject using the disclosed immunogenic conjugates, as well as methods of treating, ameliorating or preventing influenza infection, are also disclosed.
Claims22
An immunogenic conjugate comprising an influenza virus hemagglutinin 2 (HA2) fusion peptide between 9 and 20 amino acids in length covalently linked to a carrier, wherein the conjugate elicits an immune response in a subject.
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Dependencies are inferred from the claim text.