Back to results
US 2014/0234227 A1Published application
Foam formulations
AssigneeOtic Pharma Ltd.
InventorsRodrigo Yelin, Jorge Danziger, Eran Eilat
Life of this patent
Estimating the term…
Abstract
The present invention provides foamable pharmaceutical compositions comprising water-soluble antibiotics and anti-inflammatory steroids and methods of preparing same. Particularly, the present invention relates to oil-free pharmaceutical compositions comprising a quinolone, an anti-inflammatory steroid, a polar co-solvent, and propellant gas, administered to the ear in the form of foam for treating ear disorders.
Claims21
1-32. (canceled)
A foamable pharmaceutical composition comprising:
- (i) a polar co-solvent in an amount of from about 40% (w/w) to about 70% (w/w) of the composition;
- (ii) water in an amount of from about 30% (w/w) to about 60% (w/w) of the composition;
- (iii) a surfactant and/or a foaming agent;
- (iv) a stabilizing agent;
- (v) a quinolone;
- (vi) a steroidal anti-inflammatory agent;
- and
- (vii) a compressed propellant gas
- wherein the composition is devoid of oil, and wherein the composition packaged in a container is adapted to form foam after being dispensed from the container.
6 more elements
Dependencies are inferred from the claim text.