Article Comprising Calcium for Reducing the Production of TSST-1
AssigneeThe Procter & Gamble Company
InventorsThomas Ward Osborn, III, Fancheng Wang, Kimberly Ann Nemeth, Catherine Cornick Davis
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Abstract
Articles comprising one or more calcium salts are provided. The articles can contain one or more calcium salts in an amount effective to reduce the production of TSST-1 by at least about 50% when measured by the Shake Flask Method. In certain embodiments, the one or more calcium salts can be substantially non-lethal to Staphylococcus aureus when measured by the Shake Flask Method, and/or to Lactobacillus crispatus, Lactobacillus gasseri, and/or Lactobacillus iners when measured by the Maximum Tolerated Dose Test.
Claims20
A method for manufacturing a vaginal article, the method comprising the steps of:
- a. forming a tampon pledget comprising rayon fibers and/or cotton fibers, wherein the rayon fibers and/or cotton fibers include a calcium salt that was added thereto prior to formation of the tampon pledget;
- and
- b. compressing and/or shaping the tampon pledget into a finished tampon configuration that is different than that of the tampon pledget.
A method for manufacturing a vaginal article, the method comprising the steps of:
- a. forming a tampon pledget comprising rayon, wherein the rayon fibers include a calcium salt that was added thereto prior to formation of the tampon pledget;
- and
- b. compressing and/or shaping the tampon pledget into a finished tampon configuration that is different than that of the tampon pledget,
- wherein the calcium salt comprises calcium lactate and/or calcium citrate malate.
A method for manufacturing a vaginal article, the method comprising the steps of:
- a. forming a tampon pledget comprising cotton, wherein the cotton fibers include a calcium salt that was added thereto prior to formation of the tampon pledget;
- and
- b. compressing and/or shaping the tampon pledget into a finished tampon configuration that is different than that of the tampon pledget,
- wherein the calcium salt comprises calcium lactate and/or calcium citrate malate.
Dependencies are inferred from the claim text.