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US 2014/0228840 A1Published application
Composite compositions and applications thereof
AssigneeWake Forest University
InventorsJoel L. Berry, David L. Carroll, Pierre H. Rolland
Life of this patent
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Abstract
In one aspect, composite compositions are described herein. In some embodiments, a composite composition comprises an embolic agent and a plurality of nanoparticles dispersed in the embolic agent, wherein a portion of the nanoparticles are individually dispersed in the embolic agent.
Claims26
A composite composition comprising:
- an embolic agent;
- and
- a plurality of nanoparticles dispersed in the embolic agent, wherein a portion of the nanoparticles are individually dispersed in the embolic agent.
A treatment system for diseased tissue comprising:
- a source of radiofrequency energy;
- and
- a thermal induction agent operable for positioning in the diseased tissue, the thermal induction agent comprising a material having a dielectric loss factor greater than a dielectric loss factor of the diseased tissue.
A method of treating diseased tissue comprising:
- disposing in the diseased tissue a material having a dielectric loss factor greater than a dielectric loss factor of the diseased tissue to define a predetermined cellular killing zone in the diseased tissue;
- and
- providing thermal energy to the diseased tissue by exposing the diseased tissue and the material to radiofrequency energy.
A method comprising:
- reducing damage to non-diseased tissue adjacent to diseased tissue during radiofrequency thermal ablation of the diseased tissue in an ablation zone by restricting formation of an apoptotic cellular region in the non-diseased tissue resulting from the radiofrequency thermal ablation, wherein restricting comprises:
- disposing in the diseased tissue prior to application of radiofrequency energy a material having a dielectric loss factor greater than dielectric loss factor of the diseased tissue.
Dependencies are inferred from the claim text.