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US 2014/0228682 A1Published application
Imaging probes, imaging systems, and methods of imaging
OwnerHongguang Liu, Xiang Hu +2inventors
InventorsHongguang Liu, Xiang Hu, Zhen Cheng, Yang Liu
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Abstract
Embodiments of the present disclosure include methods of imaging a target area, methods of monitoring the degeneration of cartilage, and the like.
Claims20
A method of imaging a target area, comprising:
- introducing a probe into a subject, wherein the probe is capable of emitting positrons and photons;
- detecting gamma rays generated by the positrons emitted from the probe;
- and
- detecting low energy photons generated by the probe,
- wherein the origin of the gamma ray and the photons corresponds to the location of the probe, wherein the location of the probe corresponds to the location of the target area.
2 more elements
The method of claim 9, wherein the relative strength of the gamma rays and low energy photons detected corresponds to degeneration of the articular cartilage.
A method of monitoring the degeneration of cartilage, comprising:
- introducing a probe into a subject at a first time, wherein the probe is capable of emitting positrons and photons;
- detecting gamma rays generated by the positrons emitted from the probe;
- detecting low energy photons generated by the probe;
- generating a first image of a target area that includes the cartilage, wherein the origin of the gamma rays and the photons corresponds to the location of the probe, wherein the location of the probe corresponds to the location of the target area;
- repeating the steps above at a second time to generate a second image corresponding to the second time;
- and
- comparing the images produced at the first time and the second time to monitor the degeneration of the cartilage.
4 more elements
A method of imaging articular cartilage, comprising:
- introducing 89Zr oxalate into a subject, wherein the 89Zr ion is capable of emitting positrons and photons;
- detecting gamma rays generated by the positrons emitted from the 89Zr ion;
- and
- detecting low energy photons generated by the 89Zr ion,
- wherein the origin of the gamma ray and the photons corresponds to the location of the 89Zr ion, wherein the location of the 89Zr ion corresponds to the location of the articular cartilage.
2 more elements
Dependencies are inferred from the claim text.