Apoptosis signal-regulating kinase inhibitor
AssigneeGilead Sciences, Inc.
InventorGregory Notte
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Abstract
The present invention relates to a compound of formula (I): The compound has apoptosis signal-regulating kinase (“ASK1”) inhibitory activity, and is thus useful in the treatment of diseases such as kidney disease, diabetic nephropathy and kidney fibrosis.
Claims24
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A method of treating or preventing a disease or disorder mediated by apoptosis signaling-regulating kinase with a compound of formula (I)
- or a pharmaceutically acceptable salt thereof.
A method of treating or preventing a disease or disorder mediated by apoptosis signaling-regulating kinase comprising administering to a patient in need thereof a pharmaceutical composition comprising a compound of formula (I)
- or pharmaceutically acceptable salt thereof.
A pharmaceutical composition for combination treatment comprises a compound of formula (I)
- or a pharmaceutically acceptable salt thereof;
- and one or more therapeutic agent.
A method of inhibiting apoptosis signaling-regulating kinase 1 with a compound of formula (I)
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.