Benzonitrile derivatives as kinase inhibitors

Compounds of the formula I

• in which
• X denotes CH or N,
• Y denotes Het2-diyl,
• R1 denotes O(CH2)nHet1, NH(CH2)nHet1, OA, NHA, NA2, O(CH2)nCyc or NH(CH2)nCyc,
• R2 denotes H, A, Ar1, (CH2)nHet3, CN, (CH2)nCyc, CONH2, COOA, (CH2)nOH, (CH2)nOA, (CH2)nNH2, (CH2)nNHA or (CH2)nNA2,
• Ar1 denotes phenyl which is unsubstituted or mono-, di- or trisubstituted by Hal, A, OH, OA, COOH, COOA, CN, CONH2, NHSO2A, NO2, NH2, NHA, NA2, SO2NH2, SO2NHA, SO2NA2, CHO and/or SO2A,
• Het1 denotes dihydropyrrolyl, pyrrolidinyl, azetidinyl, tetrahydroimidazolyl, dihydropyrazolyl, tetrahydropyrazolyl, dihydropyridyl, tetrahydropyridyl, piperidinyl, morpholinyl, hexahydropyridazinyl, hexahydropyrimidinyl, 1,3-dioxolanyl, tetrahydropyranyl or piperazinyl, each of which is unsubstituted or monosubstituted by OH, COOA, CONH2, COA and/or A,
• Het2 denotes furyl, thienyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, isoxazolyl, thiazolyl, triazolyl, pyridyl, pyrimidyl, pyridazinyl, pyrazinyl, indolyl, isoindolyl, benzimidazolyl, indazolyl, quinolyl, 1,3-benzodioxolyl, benzothiophenyl, benzofuranyl, imidazopyridyl, 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl or furo[3,2-b]pyridyl, each of which is unsubstituted or monosubstituted by Hal, A, OH, ═O, OA, CN, COOA, COOH, CONH2 and/or NHCOA,
• Het3 denotes dihydropyrrolyl, pyrrolidinyl, azetidinyl, tetrahydroimidazolyl, tetrahydrofuranyl, dihydropyrazolyl, tetrahydropyrazolyl, dihydropyridyl, tetrahydropyridyl, dihydropyranyl, tetrahydropyranyl, piperidinyl, morpholinyl, hexahydropyridazinyl, hexahydropyrimidinyl, 1,3-dioxolanyl, piperazinyl, furyl, thienyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, isoxazolyl, thiazolyl, triazolyl, pyridyl, pyrimidyl, pyridazinyl, indolyl, isoindolyl, benzimidazolyl, indazolyl, quinolyl, 1,3-benzodioxolyl, benzothiophenyl, benzofuranyl, imidazopyridyl or furo[3,2-b]pyridyl, each of which is unsubstituted or mono- or disubstituted by Hal, A, OH, OA, CN, COOA, COOH, CONH2, CONHA, CONA2, COA, COCH2NH2, COCH2NHA, COCH2NA2, (CH2)nCyc and/or NHCOA,
• A denotes unbranched or branched alkyl having 1-10 C atoms, in which one or two non-adjacent CH and/or CH2 groups may be replaced by N, O and/or S atoms and/or, in addition, 1-7H atoms may be replaced by F and/or Cl,
• Cyc denotes cyclic alkyl having 3, 4, 5, 6 or 7 C atoms which is unsubstituted or monosubstituted by CN, (CH2)nOH or A,
• Hal denotes F, Cl, Br or I,
• n denotes 0, 1, 2, 3 or 4,
• and pharmaceutically usable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios.