Pharmaceutical compositions
AssigneeGlaxoSmithKline LLC
InventorsMark A. BUSH, Murray W. Stewart, Yonghong Yang
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Abstract
The present invention provides pharmaceutical compositions comprising at least one polypeptide having GLP-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having GLP-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention.
Claims5
A pharmaceutical composition comprising a polypeptide consisting of the amino acid sequence set forth in SEQ ID NO:1 wherein an effective dose of said pharmaceutical composition comprises 50 mg of said polypeptide.
A pharmaceutical composition consisting of about 50 mg of a polypeptide having the amino acid sequence set forth in SEQ ID NO:1, 2.8% mannitol, 4.2% trehalose dihydrate, 0.01% polysorbate 80, about 10 mM to about 20 mM phosphate buffer and water for injection.
Dependencies are inferred from the claim text.