Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions

A compound of formula (I)

• wherein
• X and Y are the same or different and are independently selected from the following:
• and
• each R is independently selected from R1 and R2, in which
• R1 and R2 are the same or different and are independently selected from 3-amino-piperidin-1-yl, (2-amino-2-methyl-propyl)-methylamino and (2-amino-propyl)-methylamino;
• or a tautomer, stereoisomer, mixture or salt thereof.