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US 2014/0227750 A1Published application
Biological methods for preparing adipic acid
AssigneeVerdezyne, Inc.
InventorsStephen PICATAGGIO, Tom BEARDSLEE
Life of this patent
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Abstract
The technology relates in part to biological methods for producing adipic acid and engineered microorganisms capable of such production.
Claims20
A method for producing adipic acid, comprising:
- (a) contacting a Candida yeast with a feedstock comprising a vegetable oil, wherein the Candida yeast comprises:
- (i) a genetic alteration that partially blocks beta oxidation activity,
- (ii) a genetic alteration that reduces or eliminates long chain acyl-CoA synthetase activity, and
- (iii) a genetic alteration that reduces or eliminates acyl-CoA synthetase activity;
- and
- (b) culturing the Candida yeast under conditions in which adipic acid is produced.
3 more elements
Dependencies are inferred from the claim text.