N-demethyase genes and uses thereof
Assigneeuniversity of Iowa Research foundation iowa centers for enterprise
InventorsVenkiteswaran Subramanian, Michael Tai-Man Louie, Ryan Summers
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Abstract
The invention provides isolated nucleic acid encoding one or more gene products that allow for degradation of caffeine and related structures, and for preparation of intermediates in that catabolic pathway. Further provided are methods of using one or more of those gene products.
Claims19
An isolated polypeptide which is a N-demethylase or a reductase, having at least 80% amino acid sequence identity to a polypeptide encoded by a polynucleotide comprising SEQ ID NO:
- 37, 38, or 39 or SEQ ID NO:43.
An isolated polynucleotide encoding a polypeptide having at least 80% amino acid sequence identity to a polypeptide encoded by a polynucleotide comprising SEQ ID NO:
- 37, 38, or 39, or SEQ ID NO:43.
A composition comprising a plurality of isolated polypeptides, wherein one of the plurality of polypeptides has at least 80% amino acid sequence identity to a polypeptide encoded by a polynucleotide comprising SEQ ID NO:
- 37, 38, or 39, or SEQ ID NO:43.
(canceled)
Dependencies are inferred from the claim text.