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US 2014/0227428 A1Published application
Preparation method for medical porous tantalum implant material
AssigneeChongqing Runze Pharmaceutical Co., Ltd.
InventorLei Ye
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AssigneeChongqing Runze Pharmaceutical Co., Ltd.
InventorLei Ye
Estimating the term…
A preparation method for medical porous tantalum implant material is provided, which includes mixing polyethylene glycol aqueous solution and tantalum powder to form tantalum slurry, casting the tantalum slurry into an organic foam body through vibrant pressurization, and going through steps of drying, degreasing, vacuum sintering and thermal treatment to obtain the porous tantalum. The solution is a 2-8 wt % polyethylene glycol aqueous solution, the frequency of vibration is 20-80 times/min, the thermal treatment is performed under 10−4-10−3 Pa of vacuity and the temperature is increased to 800-900° C. at a rate of 10-20° C./min and keeping the temperature for 240-480 minutes, then decreased to 400° C. at a rate of 2-5° C./min and keeping the temperature for 120-300 minutes, and cooled down to the room temperature naturally in the furnace. Accordingly, the porous tantalum made by the method of the present invention is a suitable for medical implantation as an alternative support of bony tissue, and assured good biocompatibility and mechanical properties. Furthermore, the reagents and the organic foam body, which are can be decomposed and resulting no residue during sintering, are used to guarantee the bio-safety of the medical porous tantalum implant material.
A preparation method for medical porous tantalum implant material, comprising:
The method as claimed in claimed 1, wherein the tantalum powder having an average diameter of less than 43 μm and oxygen content in an amount of less than 0.1%, wherein it has 40-80% of porosity and 150-500 μm of pore diameter;
The method as claimed in claimed 1 or 2, wherein 6-9 weight parts of tantalum powder and 1 weight part of the 4-5 wt % polyvinyl alcohol solution are mixed homogeneously and agitated to form the tantalum slurry.
The method as claimed in claimed 3, wherein the frequency of vibration is 60 times/min, the pressure is 0.1 Mpa, the polyurethane foam body has 0.56-0.72 mm of pore diameter, 0.025 g/cm3 of density and 50°-80° of hardness, tantalum slurry are made by mixing 7 weight parts of tantalum powder of the tantalum powder and 1 weight part of the PEG solution.
The method as claimed in claimed 1 or 2, wherein the tantalum slurry is filled into the organic foam body through vibrant pressurization, the PEG solution is sprayed uniformly on the surface of the organic foam body, and the ratio of the weight parts of the sprayed PEG solution and the tantalum powder is 1:6.
Dependencies are inferred from the claim text.