# US 2014/0227370 A1 · Polysaccharide fibres for wound dressings > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0227370 A1 - Document ID: US20140227370A1 - Status: Published application - Kind: A1 - Application number: 14/350,174 - Filed: 2012-12-05 - Published: 2014-08-14 - Earliest claimed: 2011-10-05 - Assignees: University of Bolton - Inventors: Mohsen Miraftab; Rashid Masood - Web page: https://patentgrep.com/patent/US20140227370A1 ## CPC - A61K 47/36: Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin - A61K 33/38: Silver; Compounds thereof - A61L 15/28: Polysaccharides or their derivatives {(A61L15/225 takes precedence)} - A61L 15/46: Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria - C08K 3/16: Halogen-containing compounds - C08L 5/00: Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00 - C08L 5/04: Alginic acid; Derivatives thereof - D01D 5/06: Wet spinning methods {(D01D5/0046 takes precedence)} - D01D 10/06: Washing or drying - D01F 1/103: {Agents inhibiting growth of microorganisms} - D01F 8/18: from other substances - D01F 9/04: of alginates - A61L 2300/104: Silver, e.g. silver sulfadiazine - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - C08K: Use of inorganic or non-macromolecular organic substances as compounding ingredients (paints, inks, varnishes, dyes, polishes, adhesives C09) - C08L: COMPOSITIONS OF MACROMOLECULAR COMPOUNDS (compositions based on polymerisable monomers C08F, C08G; artificial filaments or fibres D01F; textile treating compositions D06) - D01D: MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS - D01F: CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS ## Abstract A polysaccharide fibre useful in biomedical applications such as wound management is made as a bicomponent fibre with alginate and psyllium polymers. An antimicrobial silver salt may be incorporated. The fibre may be made by extruding an aqueous mixture of alkaline-solubilised psyllium and sodium alginate into a calcium chloride bath. ## Claims ### Claim 1 A polysaccharide fibre having, as components of the same fibre, alginate and psyllium polymers. ### Claim 2 (depends on 1) A fibre according to claim 1 wherein the alginate and psyllium polymers are bonded to each other. ### Claim 3 (depends on 1) A fibre according to claim 1 which is produced by extrusion or spinning of a mixture of the alginate and psyllium polymers. ### Claim 4 (depends on 1) A fibre according to claim 1 which is a bicomponent fibre containing the psyllium and alginate polymers as the only structural components. ### Claim 5 (depends on 1) A fibre according to claim 1 further including an antimicrobial substance. ### Claim 6 (depends on 5) A fibre according to claim 5 wherein the antimicrobial substance is a silver substance. ### Claim 7 An antimicrobial fibre containing alginate, psyllium and a silver substance. ### Claim 8 (canceled) ### Claim 9 (depends on 6) A fibre according to claim 6 wherein the silver substance is silver nitrate or silver carbonate. ### Claim 10 A method of making a polysaccharide fibre comprising spinning or extruding an aqueous mixture of soluble psyllium and alginate polymers into a bath containing a substance which coagulates the aqueous mixture to form a fibre. ### Claim 11 (depends on 10) A method according to claim 10 wherein the coagulating substance comprises a calcium salt which forms insoluble calcium alginate with the soluble alginate polymer of the aqueous mixture. ### Claim 12 (depends on 11) A method according to claim 11 wherein the bath contains 1-2% by weight calcium chloride. ### Claim 13 (depends on 10) A method according to claim 10 wherein the soluble psyllium polymer is solubilised in alkaline solution. ### Claim 14 (depends on 10) A method according to claim 10 wherein the soluble alginate polymer comprises sodium alginate. ### Claim 15 (depends on 10) A method according to claim 10, further including washing the formed fibre with aqueous acetone. ### Claim 16 (depends on 10) A method according to claim 10 wherein the aqueous mixture contains psyllium and alginate polymers as the sole structural polymers. ### Claim 17 (depends on 10) A method according to claim 10 further including an antimicrobial substance in the aqueous mixture. ### Claim 18 (depends on 17) A method according to claim 17 wherein the antimicrobial substance is a silver substance. ### Claim 19 (depends on 18) A method according to claim 18 wherein the silver substance is silver nitrate or silver carbonate. ### Claim 20 (depends on 10) A fibre formed by the method of claim 10. ### Claim 21 (canceled) ### Claim 22 (canceled)