Silver Oxide Formulations

A topical formulation for application to exposed body tissue, the formulation comprising:

• (a) a silver oxide,
• and
• (b) at least one inorganic whitener;
• selected from the group of inorganic whiteners consisting of an inorganic magnesium compound and an inorganic calcium compound, said silver oxide and said inorganic whitener compound intimately dispersed within a carrier medium,
• and wherein a ratio of said inorganic whitener compound, to said silver oxide, is at least 0.2:1, by weight, within the formulation.

A solid biocompatible formulation suitable for insertion within chronic and acute wounds of humans and animals, the formulation comprising a topical antibiotic, a biocompatible humectant, a biocompatible viscosity-building agent, and at least 5% water, by weight, said humectant and said viscosity-building agent intimately mixed within the formulation,

• the formulation formulated and adapted whereby the formulation remains a solid over at least an entire temperature range of 20° C. to 35° C.,
• the solid formulation having a storage modulus (G′) and a loss modulus (G″), both measured at 25° C. and within a frequency range of 0.1 Hz to 1.0 Hz, and a complex modulus (G*), defined by:
• G*=(G′2+G″2)1/2
• the formulation having at least one of the following five rheological properties:
• (1) in a torque sweep at a frequency of 1.0 Hz, said complex modulus achieves a plateau or a maximum of at least 4.0×104 Pa, at least 6.0×104 Pa, at least 8.0×104 Pa, or at least 10.0×104 Pa;
• (2) in said torque sweep, said complex modulus drops sharply, or begins to exhibit non-linear behavior, at an oscillating stress of at least 800 Pa, at least 900 Pa, at least 1000 Pa, at least 1200 Pa, at least 1500 Pa, or at least 2000 Pa;
• within said frequency range, at at least one point:
• (3) said storage modulus is at least 1.0×104 Pa, at least 2.0×104 Pa, at least 3.0×104 Pa, at least 4.0×104 Pa, at least 5.0×104 Pa, or at least 6.0×104 Pa;
• (4) said loss modulus is at least 0.4×104 Pa, at least 0.5×104 Pa, at least 0.6×104 Pa, at least 0.8×104 Pa, at least 1.0×104 Pa, at least 1.5×104 Pa or at least 2.0×104 Pa;
• (5) said complex modulus is at least 1.05×104 Pa, at least 1.05×104 Pa, at least 2×104 Pa, at least 3.0×104 Pa, at least 4.0×104 Pa, or at least 6.0×104 Pa.