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US 2014/0227367 A1Published application
Treating inflammation with a combination of an ellagitannin and hydrogen peroxide
AssigneeLiveLeaf, Inc.
InventorsALEXANDER L. HUANG, GIN WU
Life of this patent
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Abstract
The teachings provided herein generally relate to site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites. More particularly, the systems taught here include a phenolic compound bound to a reactive oxygen species, wherein the phenolic compound and the reactive oxygen species react at a target area in the presence of an oxidoreductase enzyme.
Claims30
A method of treating an inflammation in a subject, comprising:
- administering an effective amount of a binding system to a subject having an inflammation, the binding system comprising:
- an ellagitannin;
- and,
- hydrogen peroxide;
- wherein,
- the hydrogen peroxide is combined with the ellagitannin at a weight ratio that ranges from about 1:1000 to about 10:1 of the an extract to the hydrogen peroxide;
- and,
- the administering inhibits, or ameliorates the symptoms of, the inflammation of the subject.
5 more elements
A method of inhibiting a gastrointestinal-mediated autoimmune response in a subject, comprising:
- administering an effective amount of a binding system to a subject having a gastrointestinal-mediated autoimmune activity, the binding system comprising:
- an ellagitannin;
- and,
- hydrogen peroxide;
- wherein,
- the hydrogen peroxide is combined with the ellagitannin at a weight ratio that ranges from about 1:1000 to about 10:1 of the an extract to the hydrogen peroxide;
- and,
- the administering inhibits, or ameliorates the symptoms of, the gastrointestinal-mediated autoimmune activity in the subject.
5 more elements
A composition, comprising:
- an ellagitannin;
- hydrogen peroxide;
- and,
- a pharmaceutically acceptable carrier;
- wherein,
- the hydrogen peroxide is combined with the ellagitannin at a weight ratio that ranges from about 1:1000 to about 10:1 of the ellagitannin to the hydrogen peroxide.
3 more elements
A formulation, comprising:
- a punicalagin;
- hydrogen peroxide;
- and,
- a pharmaceutically acceptable excipient;
- wherein,
- the hydrogen peroxide is combined with the punicalagin at a weight ratio that ranges from about 1:1000 to about 10:1 of the an extract to the hydrogen peroxide.
3 more elements
Dependencies are inferred from the claim text.