Combination vaccine for respiratory syncytial virus and influenza
AssigneeNovavax, Inc.
InventorsGale E. SMITH, Greg GLENN, Lou FRIES, James F. YOUNG
Life of this patent
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Abstract
The present disclosure is directed to compositions and methods for raising immune responses against influenza and respiratory synctial virus by administering combination immunogenic composition against both viruses at the same time. The combination compositions contain an RSV component and one, two, three, four, or more influenza components. The combination compositions provide a greater immune response than that obtained by separately administering the RSV and influenza components.
Claims25
An immunogenic composition comprising a respiratory syncytial virus (RSV) fusion (F) component and an influenza component.
An immunogenic composition comprising a respiratory syncytial virus (RSV) fusion (F) component and three influenza components,
- wherein each influenza component comprises a VLP,
- wherein each VLP comprises an influenza M1 protein, an influenza NA protein, and an influenza HA protein;
- and
- wherein the NA protein and the HA protein in each VLP are derived from the same influenza strain,
- wherein the influenza proteins in the first, second, and third VLPs are derived from different strains than each other.
- wherein the first, second and third VLPs each comprise an M1 protein derived from the same strain.
A kit comprising a respiratory syncytial virus (RSV) fusion (F) component and at least one influenza component, wherein each component is in a separate container.
Dependencies are inferred from the claim text.