Vaccines for preventing and treating alzheimer's disease
OwnerBin Wang, Yang Yu +2inventors
InventorsBin Wang, Yang Yu, Xianzhu Zhu, Shuang Wang
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Abstract
Disclosed herein are vaccines comprising an amyloid beta antigen and a nucleic acid encoding the amyloid beta antigen, or a variant thereof. T cell proliferation can be inhibited and iTreg cells can be stimulated in the subject administered the vaccine. Further provided are methods for treating Alzheimer's Disease, methods for reducing or slowing the rate of formation of amyloid beta plaques, methods for treating encephalitis, and methods for of reducing brain swelling. The methods can comprise administering the vaccine to a subject in need thereof.
Claims25
A vaccine comprising an amyloid beta antigen and a nucleic acid encoding the amyloid beta antigen, or a variant thereof.
Dependencies are inferred from the claim text.